Co-Bodies
Definition: "a molecule in which two or more distinct and different binding sites complementary to distinct and different epitopes on one and the same target, are linked together in such a way that all can bind at the same time".
Co-bodies improve accuracy and dependability of choice, as it were by using several different pieces of evidence at the same time instead of only one. In a synthetic co-body two DIFFERENT antibody binding units may be connected by a flexible nucleic acid chain so that both act without distorting either themselves or the target.
An Introduction to Co-Bodies.pdf more fully explores the concept and the applications possible by using two or more binding reactions together to identify another molecule, while Semi-synthetic antibody molecules having enhanced affinity and selectivity.pdf describes the essential invention in a straightforward way useful to biochemically-aware readers.
For insights into the way research has developed our knowledge of the phenomenon, please go to http://www.trcboyde.net/publications-co-selection-co-bodies-co-affinity.html.